Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data. Plaquenil induced rash Plaquenil side effects anemia Fatal dose of chloroquine Chloroquine resistant malaria meaning Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. Plaquenil stays in your body for about 3 months. If you must stop it, it will take a while for the side effects to go away. You should have an eye examination every year to prevent a very rare but serious eye problem. Less than one person in 5,000 develops the problem. Please check with the appropriate physician regarding health questions and concerns. The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Hydroxychloroquine how long does it stay in body Hydrochlorothiazide - how long does it take to eliminate in., Taking Plaquenil for Rheumatoid Arthritis Aao guidelines for plaquenil How long for plaquenil rash to end - I started plaquenil in January and I started with a severe rash covered about 70% of body in May. My Rheumy had me stop taking plaquenil after 1 week of the rash getting worse. Bone Joint Muscle - Arthritis how long for plaquenil rash to end. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. How long does Hydroxychloroquine stay in your system?. Hydroxychloroquine doesn’t work immediately. It may be 12 weeks or longer before you notice any benefit. Because it's a long-term treatment it's important to keep taking hydroxychloroquine unless you have severe side-effects even if it doesn't seem to be working at first even when your symptoms improve. Let me tell you what weaning down from Plaquenil. to do to stay as healthy as possible for as long as possible. on the plaquenil. I am concerned that my body. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.