Alternatively, we suggest using this opportunity to take a little break from work and read some of the interesting articles below. There are various types of cutaneous LE, classified as acute, subacute, intermittent and chronic cutaneous LE. Can plaquenil cause a rash Chloroquine ph 250 mg tablet Chloroquine lupus treatment In patients with cutaneous lupus erythematosus CLE and mild skin involvement, local therapy consisting of topically applied pharmacological agents, e.g. topical/intralesional steroids, may be su. A randomized, double‐blind, multicentre study was performed to compare the efficacy of acitretin 50 mg/day with hydroxychloroquine 400 mg/day in 28 and 30 patients, respectively, suffering from cutaneous lupus erythematosus LE. The study was carried out over an 8‐week period. Cutaneous lupus erythematosus CLE is a form of lupus that predominantly affects the skin. The most common forms are subacute cutaneous lupus erythematosus SCLE and discoid lupus erythematosus DLE. There is a very small chance that these cutaneous forms of lupus may develop into systemic lupus erythematosus SLE with internal organ. Acute cutaneous LE affects at least 50% of patients with systemic lupus erythematosus (SLE). Specific features of acute cutaneous LE may include: See more images of systemic lupus erythematosus. The revised Cutaneous Lupus Erythematosus Disease Area and Severity Index (RCLASI) can be used to assess disease activity and damage. Treatment of cutaneous lupus erythematosus with acitretin and hydroxychloroquine Treating Lupus with Anti-Malarial Drugs Johns Hopkins., Treatment of cutaneous lupus erythematosus with acitretin. Chloroquine solubilityPlaquenil light sensitivity In patients with cutaneous lupus erythematosus CLE and mild skin involvement, local therapy consisting of topically applied pharmacological agents, e.g. topical/intralesional steroids, may be sufficient. Recent reports have also shown efficacy of topical calcineurin inhibitors in patients with CLE, particularly on the face. Treatment of cutaneous lupus erythematosus - A. Kuhn, F.. ACD A-Z of Skin - Cutaneous lupus erythematosus. Cutaneous Lupus Erythematosus Diagnosis and treatment. The emphasis is on symptomatic treatment and only very rarely is it necessary to resort to high-dose systemic steroids or immunosuppressive agents for skin disease per se. Treatment of the skin in lupus often needs a multidisciplinary approach. Hydroxychloroquine and chloroquine phosphate have shown beneficial effects in treating discoid lupus erythematosus DLE. Additionally, The antimalarial drugs may prevent the development of systemic lupus erythematosus SLE in patients with DLE, and they might decrease the risk of cardiovascular disease. Mar 17, 2019 Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye.