Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Is chloroquine injection safe in early pregnancy Plaquenil toxicity ideal body weight Fundus autofluorescence patterns in various stages of hydroxychloroquine retinopathy. Classic bull’s-eye maculopathy appearance A. As the RPE atrophies, the FAF intensity in the pericentral macula changes to a mottled, or speckled appearance B, and eventually coalesces into dark areas of absence of FAF signal once the cells have died C. Chloroquine, hydroxychloroquine, fundus autofluorescence imaging, multifocal electroretinogram, optical coherence tomography, toxic maculopathy Search for Similar Articles You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search. Unusual Fundus Autofluorescence Appearance in a Patient with Hydroxychloroquine Retinal OCT of the right top and left eye bottom showing outer retina and retinal pigment epithelium changes and foveal thinning. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Fundus autofluorescence in hydroxychloroquine toxicity Determine risk for hydroxychloroquine retinal toxicity., FUNDUS AUTOFLUORESCENCE FINDINGS IN EARLY CHLOROQUINE. Plaquenil eye irregularityCan i immediately stop plaquenilPlaquenil eye floatersPlaquenil skin issues Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1 Hydroxychloroquine toxicity - EyeWiki. PDF Unusual Fundus Autofluorescence Appearance in a.. Unusual Fundus Autofluorescence Appearance in a Patient.. Fundus autofluorescence FAF imaging is a novel in-vivo imaging method assessing the distribution of lipofuscin in the outer retina, subretinal space, and RPE. 14 Fundus Autofluorescence FAF Early hydroxychloroquine toxicity can also be detected on autofluorescence as an increased ring of signal within the parafoveal and extramacular regions, which is indicative of photoreceptor dysfunction and RPE dysfunction. Jun 06, 2015 To report an unusual fundus autofluorescence aspect in a patient with suspected hydroxychloroquine retinal toxicity. Method Case report of an unusual presentation of a patient treated for 9 consecutive years with a therapeutically recommended dose of hydroxychloroquine.