Most importantly, you help support continued development of this site. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine (Plaquenil). This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day (200 bid). Chloroquine torsades Does plaquenil treat ckd Hydroxychloroquine efectos secundarios Plaquenil works This apparently resulted in overdosing of thin patients. Thus, the patient’s real weight is now recommended as the basis for calculating the daily dose per weight in kg. Doses ≥ 5 mg/kg/day real weight of hydroxychloroquine 2.3 mg/kg/day of chloroquine are associated with higher risk of toxicity. Ideal Body Weight for Calculating Hydroxychloroquine Dosage. The most important risk factor for hydroxychloroquine retinopathy is the daily dose of the drug. If a patient is overweight, one should use the ideal body weight to assess whether the doaily dose is in the toxic range /= 6.5 mg/kg/day. Diseases. It is believed that hydroxychloroquine interferes with communication of cells in the immune system. SIDE is rare. It is recommended that you have an eye exam EFFECTS HOW TO TAKE IT Hydroxychloroquine comes in an oral tablet. Adult dosing ranges from 200mg or 400mg per day 5 mg per kg of actual body weight. In some cases, higher doses It now solely uses real body weight (rather than ideal body weight) based on new recommendations from a 2014 study (1). Disclaimer: This tool is designed to help eye care professionals better understand the risk the of retinotoxicity from hydroxychloroquine. Please note: This calculator was modified in 9/2015. Hydroxychloroquine dose per kg Recommendations on Screening for Chloroquine and., Ideal Body Weight for Calculating Hydroxychloroquine Dosage. Plaquenil dark skinHydroxychloroquine and lung cancerFundus autofluorescence in hydroxychloroquine toxicity2d structure of chloroquine Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Drug spotlight on hydroxychloroquine Lupus Foundation of.. PATIENT FACT SHEET Hydroxychloroquine Plaquenil. Hydroxychloroquine Uses, Dosage & Side Effects -. Hydroxychloroquine is dosed according to body weight. The American Academy of Ophthalmology AAO currently defines an overdose of hydroxychloroquine as more than 5.0 milligrams mg per kilogram kg of body weight 1 kg equals 2.2 pounds or more than 400 mg a day. In summary, hydroxychloroquine-induced retinal toxicity is likely more prevalent than previously believed. Once thought to be safe at a daily dose of 6.5mg/kg/day 16, newer studies show that many years of hydroxychloroquine treatment at a "safe dose" can still lead to toxicity 6. Newer guidelines state that daily dose 5mg/kg of real. All patients in the cohort were prescribed hydroxychloroquine not to exceed a dose of 6.5 mg per kilogram. The maximum daily dose prescribed is 400 mg. In those who are on hemodialysis 200 mg was prescribed after each dialysis session.