If blood flow to these bone cells greatly decreases, the cells may die, causing the bone to collapse. Osteonecrosis can lead to pain, arthritis and limited use of affected joints. Some people may even need joint replacement surgery. Hydroxychloroquine eye dots G6pd plaquenil Lupus can affect any part of the body, including the bones and bone tissue. Two especially common complications of lupus on the bones are osteoporosis and avascular necrosis. Osteoporosis is a condition in which the bones become less dense and more likely to fracture. Studies have found an increase. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Bone fractures and bone collapse due to the death of bone tissue, called avascular necrosis. Plaquenil can treat symptoms such as joint pain, mouth ulcers and skin rashes, and reduce the need. Less often affected spots are the shoulders, hands and feet. This can result in ulcers (sores) of gum tissue, exposed jaw bone and pain. Osteonecrosis, which is also called avascular necrosis (AVN) or aseptic necrosis, is the death of bone cells due to decreased blood flow. This collapse of bone, in turn, can lead to degenerative arthritis (also called osteoarthritis) of nearby joints, most often the hips and knees. Can plaquenil cause bone avascular What is Avascular Necrosis & Can It Heal On Its Own?, Plaquenil Side Effects Common, Severe, Long Term - How to pronounce chloroquineChloroquine and fluoroquinolone dissertationWhen should you take plaquenilHydroxychloroquine lichen planopilarisHow longbto take plaquenil after alcohol Summary Aseptic necrosis is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Fosamax, and have Osteoporosis. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food. Will you have Aseptic necrosis with Plaquenil - eHealthMe. Lupus Symptoms, Causes and Treatment U. S. News. Prednisone Johns Hopkins Vasculitis Center. I already got severe avascular necrosis of my joints from. June 9, 2016 ". It is certain that plaquenil does not cause systemic Lupus in humans, at least in 99.99 percent of cases. Plaquenil has been used by so many people for so many years that if it caused Lupus, this would be known by now. Plaquenil may interact with acetaminophen, cancer medications, tuberculosis medications, birth control pills or hormone replacement therapy, arthritis medications, ACE inhibitors, antibiotics, antifungals, cholesterol medications, HIV/AIDS medications, NSAIDs non-steroidal anti-inflammatory drugs, or seizure medications. Tell your doctor all medications you use. Gaucher’s disease is an inherited condition that causes an enzyme deficiency. This deficiency affects the GCase enzyme and increases a patient’s risk of avascular necrosis. Gaucher’s disease causes diminished blood flow to the bones, and patients often experience bone pain that may be severe.