This drug is often tried on patients with sarcoidosis. For some, it helps, but for others, like myself, it did nothing. Hydroxychloroquine liver function tests Plaquenil ulcerative colitis For treating sarcoidosis. Chloroquine. Another antimalarial agent, chloroquine is used for cutaneous and pulmonary sarcoidosis. It has a high-er rate of gastrointestinal and ocular toxicity than hydroxy-chloroquine, so it is used less frequently. Tetracycline derivatives. Minocycline and doxycycline have been reported as useful for cutaneous sarcoidosis. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat. The drug chloroquine is bactericidal for Bacillus megaterium ; it inhibits DNA and RNA biosynthesis and produces rapid degradation of ribosomes and dissimilation of ribosomal RNA. Inhibition of protein synthesis is also observed, evidently as a secondary effect. Inhibition of DNA replication is proposed as a general mechanism of the antimicrobial action of chloroquine. I was on Prednisone (reducing from 50 mg dose) for about 4 months which gave me clean lung x-rays - but hated the side effects. As an aside, it is the drug used to treat and prevent malaria, in case you have any travel plans I have been on chloroquin 500 mg for about the last 18 months. Chloroquine moa sarcoid Aralen chloroquine Malaria Drug Side Effects & Dosage, Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs Rheumatoid arthritis methotrexate versus hydroxychloroquinePainful muscle spasms from plaquenilCan plaquenil cause diarrheaPlaquenil and valacyclovirHydroxychloroquine cause hair loss Conclusions Chloroquine and hydroxychloroquine are effective in controlling neurological sarcoidosis in those patients who fail to respond to corticosteroids or develop severe side effects. Ocular toxic effects from chloroquine or hydroxychloroquine were not observed. CORTICOSTEROIDS are the cornerstone of therapy for neurosarcoidosis. Effectiveness of Chloroquine and Hydroxychloroquine in.. Chloroquine Mode of Action Science. Chloroquine - Sarcoidosis - Inspire. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. The clinical usefulness of chloroquine, and in some recent cases of quinine as well, has been much reduced by the evolution and spread of chloroquine resistant malaria parasites. The mechanism of resistance involves a reduced accumulation of the drug, although again the mechanism involved is controversial.