Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxychloroquine with all of your drugs and health problems. Hla-dr4 rheumatoid arthritis and hydroxychloroquine Plaquenil and trintellix interactions Every Rheumatologist I’ve had were quick to recommend all kinds of meds for my issues like prednisone, methotrexate, Imuran, Plaquenil, gabapentin, Prozac, and Ibuprofen but minimized the side effects of such medications. If you really want to treat your skin rash once and for all. Hello If it isn't possible to contact the rheumy for advice then I would want to stop the Plaquenil to see if the rashes start going away. It does sound rather worrying certainly unpleasant to experience and possibly clinically ill advised to keep taking it in these circumstances. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. For all uses of hydroxychloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Plaquenil itchy rash Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil rash or something else? Lupus Forums at The Lupus. Hydroxychloroquine azathioprine gout Take hydroxychloroquine with food or milk. Swallow whole. Do not chew, break, or crush. Keep taking hydroxychloroquine as you have been told by your doctor or other health care provider, even if you feel well. Do not take antacids or kaolin within 4 hours of hydroxychloroquine. What do I do if I miss a dose? Hydroxychloroquine Indications, Side Effects, Warnings -. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Anyone Get An Itchy Rash From Plaquenil. -. Talk to your doctor. Plaquenil hydroxychloroquine is associated with a variety of rashes, and you should discuss with your doctor if a medication change would be the best treatment for your rash. I wonder if the commencement of the skin rashes and itching is related in some way to this decreased effectiveness of the medication too. So far from the other posts it may seems that Plaquenil may be somehow associated with skin rash that looks like small hives and patchy itchiness. How do I control the itchiness of the rash? I was diagnosed a week ago with lupus, & have been on the plaquenil since then too. Today I called the clinic that I use, & left a question for my doctor, for them to ask if I needed to increase my dose, needed something else, or just wait it out, & give it more time to work.