It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine 4 cream Plaquenil and lovenox It may increase your risk of side effects. Taking cyclosporine with hydroxychloroquine can increase the amount of cyclosporine in your body. This may increase your risk of side effects from cyclosporine. Disclaimer Our goal is to provide you with the most relevant and current information. Excess body fat is another major contributor to inflammation. 4. Eat antioxidant-rich foods. Free radicals are highly reactive compounds that can damage the cells of your body and create and contribute to chronic inflammation. Antioxidants are able to neutralize these free radicals to reduce inflammation. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. If you have lupus, it may also improve the rash. It may be as long as 12 weeks before you notice the benefits. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Reducing inflammation without plaquenil Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus., Natural Ways To Reduce Inflammation In Your Body Can plaquenil be crushed Aug 14, 2017 Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Hydroxychloroquine Side-effects, uses, time to work. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. What I mean is He might want to consider taking a lower dose of Plaquenil. This won't suppress his immune system quite as much but it also won't completely control his Sjogrens. He will have to learn to live with the symptoms though they shouldn't be as bad as without Paquenil and it's surely better than death! I am sorry to hear you can't take plaquenil, it's a great med and I can't go without it. I have heard toxicity is very rare and usually only happens if you've been on plaq for many many years 20+ or take it in high doses, more than the standard 400 mg.