Treatment of discoid lupus erythematosus with chloroquine

Discussion in 'Chloroquin' started by mbit, 20-Mar-2020.

  1. Treatment of discoid lupus erythematosus with chloroquine


    Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality.

    Hydroxychloroquine hyperpigmentation Leukemia and plaquenil

    Leukopenia, which frequently occurs in patients with systemic lupus erythematosus, is usually not severe i.e. white blood cell count of less than 1,000 × 10 3 per mm 3 1.0 × 10 9 per L and rarely requires treatment. Thrombocytopenia, if stable, and if the platelet count remains above 50,000 × 10 3 per mm 3. Oral thalidomide has increasingly been accepted as a treatment for cutaneous lupus erythematosus CLE, including DLE lesions, that have not responded to other treatments. Stevens RJ, Andujar C, Edwards CJ, et al. Thalidomide in the treatment of the cutaneous manifestations of lupus erythematosus experience in sixteen consecutive patients. Systematic administration of chloroquine in discoid lupus erythematosus reduces skin lesions via inhibition of angiogenesis.

    Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids.

    Treatment of discoid lupus erythematosus with chloroquine

    An update on the use of hydroxychloroquine in cutaneous., Discoid lupus erythematosus - Treatment algorithm BMJ.

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  7. Two cases of subacute disseminated lupus erythematosus were also treated with chloroquine sulphate with no satis-factory clinical response. Summary and Conclusions Eighteen cases of chronic discoid lupus erythematosus were treated with chloroquine sulphate by mouth. The results are tabulated and discussed.

    • MEDICAL CHLOROQUIE SULPHATE TREATMENT OF CHRONIC DISCOID..
    • Systematic administration of chloroquine in discoid lupus..
    • Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus..

    User Reviews for Plaquenil to treat Systemic Lupus Erythematosus. The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Discoid lupus erythematosus DLE is a form of lupus that mainly affects your skin. DLE is different from systemic lupus erythematosus SLE, the most common form of lupus, which can affect any part of the body. Aug 21, 2018 Hydroxychloroquine is the first-line systemic agent for discoid lupus erythematosus DLE, whereas chloroquine is considered second-line antimalarial therapy in the United States.

     
  8. Mike Di Moderator

    The service provides the following types of documents: Summaries of Product Characteristics (SPCs) is a description of a medicinal product’s properties and the conditions attached to its use. It is used by healthcare professionals, such as doctors, nurses and pharmacists. Hydroxychloroquine-related retinal toxicity Rheumatology. O39 Implementing screening for hydroxychloroquine ocular. Hydroxychloroquine and Risk of Diabetes in Patients With.
     
  9. Omen Guest

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Medicines for the Prevention of Malaria While Traveling. Aralen Chloroquine Uses, Dosage, Side Effects. CHLOROQUINE PHOSPHATE, USP
     
  10. freepornonline Well-Known Member

    Lupus and Mental Health Concerns Outward effects of the disease or its treatment. Visible problems such as a facial rash or weight gain from corticosteroids used to treat lupus can affect your physical appearance and self-esteem. Work and activity limitations. Pain, fatigue, and other symptoms can make it difficult to do things you once enjoyed.

    Anxiety, depression and suicidal ideation in patients with.