It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Hydroxychloroquine diarrhea Plaquenil screening eye exam The present communication reports a series of chloroquine-induced psychosis in a clear sensorium simulating affective illness, such as mania, mixed affective states, or depression. The psychosis disappeared after cessation of the drug, combined with or without the use of low dosage phenothiazines in excited patients. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. However, following an identical dose of hydroxychloroquine and chloroquine, tissue levels of chloroquine are 2.5 times those of hydroxychloroquine. Psychosis likely induced by hydroxychloroquine in a patient with chronic Q fever a case report and clinically relevant review of pharmacology. Das P1, Rai A2, Chopra A2, Philbrick K2. Author information 1Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Das psychosis induced by hydroxychloroquine Plaquenil Side Effects Common, Severe, Long Term -, Hydroxychloroquine DermNet NZ Plaquenil for oa Severe infections are associated with an increase in the risk of developing substance-induced psychosis, according to a recent study published in the American Journal of Psychiatry. No studies. Infections—a Risk Factor for Developing Substance-Induced.. Psychosis likely induced by hydroxychloroquine in a patient.. Neuropsychiatric clinical manifestations in elderly patients.. Substance-induced psychosis commonly known as toxic psychosis is a form of substance use disorder where psychosis can be attributed to substance use. It is a psychosis that results from the effects of chemicals or drugs, including those produced by the body itself. Psychosis likely induced by hydroxychloroquine in a patient with chronic Q fever a case report and clinically relevant review of pharmacology. Das P, Rai A, Chopra A, Philbrick K Report low blood pressure hypotension, especially if patient experiences dizziness, fatigue, or other symptoms. Monitor changes in personality, mood, and behavior, including aggressiveness, anxiety, confusion, irritability, and psychosis. Notify physician if these changes become problematic.