Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine tablets ip hcqs-400 Hydroxychloroquine dry eyes Concordia plaquenil Manufacturer coupons for hydroxychloroquine If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1 Hydroxychloroquine retinopathy. It is known that some people who take. hydroxychloroquine for more than five years and/or in high doses are at increased risk of. damage to their retina, the light sensitive layer of cells at the back of the eye. This is known as. retinal toxicity or retinopathy. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Eye toxicity hydroxychloroquine Chloroquine and HydroxyChloroquine Toxicity ROQUE Eye., Hydroxychloroquine toxicity - EyeWiki Hydroxychloroquine and slurred speechIs plaquenil used to treat osteoarthritis The actual incidence of retinal toxicity from hydroxychloroquine is difficult to pin down because there is usually a long time between being started on the drug and the start of any identifiable retinal toxicity. The overall rate of probable retinal toxicity is in the range of 1 of every 200 people treated. What can Hydroxychloroquine Plaquenil do to my eyes?. Eye screening for patients taking hydroxychloroquine Plaquenil®. Hydroxychloroquine toxicity Eye News. On examination, a telltale sign of hydroxychloroquine toxicity is a bilateral change in the retinal pigment epithelium of the macula that gives the commonly described appearance of a bull’s-eye. This is a late finding, however, and too late for screening to be useful. We now know that bull’s-eye maculopathy is a late finding and may be associated with vision loss. Asians have a slightly different clinical presentation 3-4. Several recent studies have shown that instead of the classic perifoveal changes typical of hydroxychloroquine toxicity, Asians with retinal toxicity have a more peripheral pattern. Hydroxychloroquine HCQ is efficacious for various diseases 1,2, but can produce “bulls-eye” retinopathy that decreases vision even after discontinuance 3,4. Retinopathy can be present in 7.5% of patients after 5 or more years of HCQ treatment, increasing to 20% after 20 years 2.