In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Chloroquine causes elevated prolactin levels How does plaquenil work for arthritis I have been on plaquenil for a while now and have started to have blurred vision. I have been to my eye doc. twice and all tests are normal. Should I continue to take it, I know that it can cause eye problems but my doc. says that it is very rare. Patients using plaquenil may experience important but rare side effects that affect the eyes, including damage to the retina back of the eye, cornea front of the eye, and eyelids. These side effects typically occur on high doses of the medication and increase with duration of use. In rare cases, hydroxychloroquine can cause visual changes or loss of vision. Such vision problems are more likely to occur in individuals taking high doses for many years, individuals 60 years or older, or those with significant kidney disease. At the recommended dose, development of visual problems due to the medication is rare. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. How does plaquenil affect vision Hydroxychloroquine toxicity - EyeWiki, Plaquenil - Colorado Springs Eye Clinic Plaquenil for lupus nephritisChloroquine cancer clinical trial If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell. Common and Rare Side Effects for Plaquenil Oral. Hydroxychloroquine Plaquenil. Plaquenil Side Effects on Your Eyes and Vision. Plaquenil is a drug used to treat Rheumatoid Arthritis and Systemic Lupus Erythematosis. It is a very good drug and gives many patients significant relief from their symptoms. Plaquenil related eye complications are not common. Plaquenil can produce pigment changes in the macula of the retina. Then, when you stop the drug, the damage won’t progress enough to cross the fovea and affect reading vision.” Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity.