In particular, when utilized in psoriatic arthropathy, they have been reported to induce pustular eruption (2), erythroderma (3) and pustular psoriasis (4). We report here a patient with psoriasis and subacute cutaneous lupus erythematosus (SCLE) who was treated successfully with hydroxychloroquine. Plaquenil hair regrowth Contraindications plaquenil and baking soda Disease-modifying anti-rheumatic drugs DMARDs are effective at reducing inflammation associated with psoriatic arthritis PsA. There are different types of DMARDs traditional or non-biologic, biologic, and target-specific. These drugs work to slow and prevent damage to joints, enabling people with PsA to maintain function and quality of life. That’s why methotrexate is known as a disease-modifying antirheumatic drug DMARD. Many rheumatologists use methotrexate as first-line therapy for patients with rheumatoid arthritis RA, psoriatic arthritis PsA and juvenile idiopathic arthritis. Methotrexate isn’t new – it’s been part of RA treatment for more than three decades. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. If you have lupus, it may also improve the rash. It may be as long as 12 weeks before you notice the benefits. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. CASE REPORT A 66-year-old woman had vitiligo for 40 years and psoriasis for 30 years with lesions localized on the extensory face of her elbows. A critical review of the literature casts some doubts on the contraindication of antimalarials in psoriasis. Methotrexate and plaquenil for psoriatic arthritis Plaquenil for Psoriatic Arthritis? - Psoriasis - Inspire, Understanding Methotrexate Arthritis Foundation Chloroquine retinopathy guidelinesHydroxychloroquine wr walter reed In the randomized placebo-controlled trial, the Methotrexate in Psoriatic Arthritis trial MIPA, MTX was not effective overall for improving synovitis; however, there was significant efficacy in the patient and physician global assessments, and Psoriasis Area and Severity Index PASI scores at 6 months, and also efficacy for peripheral arthritis in subsets of patients with more polyarticular disease at enrollment Kingsley et al. 2012. Psoriatic arthritis latest treatments and their place in therapy. Hydroxychloroquine Side-effects, uses, time to work. New Shingles Vaccine Great News for RA Community.. Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. When the first biologic DMARD received FDA-approval in 1998, and as other biologics followed in subsequent years, it appeared as though Plaquenil would become less prescribed. Methotrexate, an immunosuppressive drug, is FDA-approved for treating psoriasis, and is used widely and successfully for treating psoriatic arthritis and rheumatoid arthritis. It can be effective at relieving the symptoms associated with psoriatic arthritis, and it may help prevent joint destruction. Compare Methotrexate vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction.