Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil for rheumatoid arthritis pain Plaquenil ophtalmo Allergic to plaquenil lupus Chloroquine 750 mg So back to the Sjogren's World Forums participant this person noticed that after beginning to take Plaquenil, it became more difficult to keep her diabetes in control occasionally her blood sugar became too low and she had symptoms of hypoglycemia feeling very anxious, tremor, feeling suddenly very hungry, perspiring heavily, and feeling faint. Several others chimed in, many of whom were not diabetic, and said that they noticed the same thing. Blood sugars will go lower than they were prior to eating breakfast if you do not include protein or the amino acids that esstentially will make up a complete protein. Of course, if your typical breakfast is the same as before your Plaquenil use began then the Rx might be invovled---or some progression or improvement of your condition. Therefore, fasting blood glucose and HbA1c levels should be monitored during the first 6 months of treatment for symptomatic and asymptomatic patients, respectively. We came to notice that our patient was suffering mild symptoms of hypoglycaemia, only after he had started receiving HCQ for RA treatment. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil causing low blood sugar Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Plaquenil and low blood sugar - Sjogren's World Plaquenil for erythema nodosumHydroxychloroquine sulfate and hydroxychloroquine sulfate plaquenil Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar. Hydroxychloroquine Oral Route Precautions - Mayo Clinic. Hypoglycaemia induced by hydroxychloroquine in a non-diabetic.. Plaquenil Hydroxychloroquine Side effects, Images, Uses.. Hydroxychloroquine HCQ, a commonly used antimalarial drug in rheumatic diseases, has shown favorable metabolic effects on both glucose control and lipid profiles. We describe a case of a young woman with type 1 diabetes whose glycemic control was optimized. Plaquenil helps most people with rheumatoid arthritis, SLE, DLE, treatment of malaria and the control of malaria symptoms, but it may have unwanted side effects in a few people. All medicines can. Symptoms of low blood sugar such as sudden sweating, shaking, rapid heartbeat, tingling in the hands/feet; Tell your doctor immediately if any of the above rare but very serious side effects occur. This is not a complete list of possible side effects. If you notice any other unusual effects not listed above, contact your doctor or pharmacist.