The cramping, cold sweats, and explosive diarrhea was unimaginable. Its my classic reaction to all new psych drugs and new antiseizure drugs, including neurontin. It is a pain in the you kno what, but I have to do what I have to do! I thought I was going to pass out the pain was so bad. Plaquenil itself I've never had an issue with, but there was a med I was given for a UTI that I didn't know was NOT supposed to be with food that gave me that kind of reaction. I wasn't too bad with Plaquenil until I doubled the dose a few weeks ago to 400mg. Plaquenil cost walmart Plaquenil 100mg tablets What are the side effects of Plaquenil? The most common side effects are diarrhea, nausea, vomiting, headache, dizziness, skin rash or black spots when you look at things. Most side effects will go away when your body gets used to the medicine. Tell your doctor if you have these side effects. A lower dose may stop them. As for the the tummy issues with Plaquenil that is probably the most common side effect with this drug. Normally, most patients get used to this drug and the tummy issues go away. Glad to hear that you're feeling some of the good side effects from the drug. It can take up to the full six months before Plaquenil to fully kick in. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. You will likely have to take additional medications to keep your rheumatoid arthritis in control. Hopefully, it's like Lynwood said - a one time anomaly. I didn't think it was going to be like this though! I really have to shift the burden off my liver whenever I can. Love, Marji I am going on week three with the plaq and I have worked out a little routine. I did give myself a much needed cleanse though..... You might want to check the website it's a great drug interaction website that also checks some foods & seasonings Sorry you had that nasty episode, I bet it's a one-time combo of some kind that did you in. Then I had explosive diarrhea I've settled down a bit but about once a week I have a really bad blow out. But I'm starting to feel a lot better with my other symptoms, so a little digestive discomfort is worth it I suppose. Hydroxychloroquine side effects diarrhea Common and Rare Side Effects for Plaquenil Oral, Plaquenil = explosive diarrhea - Amaurosis fugax from plaquenilPlaquenil and swollen lymph nodesGreater mekong subregion chloroquine resistance Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions, Pictures, Warnings.. Plaquenil hydroxychloroquine Basics, Side Effects & Reviews.. Plaquenil, diarrhea and weight loss?. I suspect plaquenil for giving me some episodic diarrhea. I am 100 mg dose and take it with my supper. Did they happen to anyone else and did it eventually stop with the diarrhea side effect? It helps so much with the fatigue and pain. I have a sensitive stomach and perhaps I shouldn't have eaten that salad for lunch yesterday. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. Does Hydroxychloroquine Have Side Effects? Like all medications, there is the risk of side effects. Fortunately, the problems seen by people taking this medication are usually very mild. Serious side effects are rare. Overall, most people who have any noticeable side effects from hydroxychloroquine experience diarrhea or nausea.