The 5-nitroimidazoles are more effective in the latter context, but when they are not available it is justifiable to use chloroquine instead. Chloroquine is more frequently used as an adjunct to dehydroemetine in the treatment of hepatic abscess. Chloroquine phosphate during pregnancy Reviews on plaquenil for lupus In treatment of amoebic liver abscess, chloroquine may be used instead of or in addition to other medications in the event of failure of improvement with metronidazole or another nitroimidazole within 5 days or intolerance to metronidazole or a nitroimidazole. Administration. Chloroquine is currently administered orally when used as a prophylaxis for malaria, as well as for the treatment of chronic autoimmune diseases. For malaria prophylaxis, 500 mg is typically administered orally two weeks before, during, and up to 8 weeks after exposure to an endemic area, taken as a weekly dose. G chloroquine phosphate 600 mg base orally once a day for 2 days, followed by 500 mg chloroquine phosphate 300 mg base orally once a day for at least 2 to 3 weeks Comments -Treatment is usually combined with an effective intestinal amebicide. Absorption from the gastrointestinal tract is efficient and peak plasma concentrations occur within 2-3 hours. It is claimed to increase the prospect of cure during the first course of treatment. Medication likely administered with chloroquine for amebiasis Chloroquine West-ward Pharmaceutical Corp FDA Package Insert, Chloroquine - StatPearls - NCBI Bookshelf Plaquenil dose based on weightTaking plaquenil with imuran On day 3 of chloroquine therapy, she developed localized brisk bullous eruptions in the irradiated area, which developed into a patch of fulminant moist desquamation. After radiotherapy was withheld for 1 week, the moist desquamation had almost healed. Chloroquine seemed to be the most probable cause for the adverse event. Psychiatric Chloroquine Side Effects Common, Severe, Long. -. Chloroquine Dosage Guide with Precautions -. Chloroquine MedlinePlus Drug Information. Chloroquine is still widely used against the three other species of plasmodium and to treat autoimmune disorders and some cases of amebiasis, an intestinal infection caused by the amoeba Entamoeba histolytica. Anti-malaria drug being tested for efficacy against COVID-19 The trials show that the drug helps patients with fever, improves lung function and recovery time. Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine is used to treat and to prevent malaria. Chloroquine is also used to treat amebiasis infection caused by amoebae.