Hydroxychloroquine induced cardiomyopathy a case report

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  1. slaveofmoney XenForo Moderator

    Hydroxychloroquine induced cardiomyopathy a case report


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    Malaria chemoprophylaxis chloroquine phosphate tablet 500 mg in the news Chloroquine counterindications

    Hydroxychloroquine HCQ is a 4-aminoquinoline which differs from chloroquine CQ in the addition of a hydroxyl group. Initially used as antimalarials, both drugs have now become mainstays in the management of rheumatic diseases principally systemic lupus erythematosus SLE and rheumatoid arthritis RA. In the last two years, CARM has received two reports of ophthalmological reactions associated with hydroxychloroquine. Of the two reports, one report was of scotoma and one report was of retinal disorder. Retinopathy is a serious adverse reaction due to the progressive and irreversible nature of the changes. The second report describes the first case of hydroxychloroquine cardiomyopathy described in a patient with scleroderma. These novel findings will add to the present knowledge of hydroxychloroquine-induced cardiomyopathy in its pathology and its implication for treatment of rheumatic diseases.

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    Hydroxychloroquine induced cardiomyopathy a case report

    Hydroxychloroquine-induced cardiomyopathy a case report. - Abstract., Risks of Hydroxychloroquine

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  6. Hydroxychloroquine HCQ-induced cardiomyopathy is one of the rare but severe complications following prolonged HCQ use. However, the exact mechanism of HCQ cardiotoxicity remains unclear and it is difficult to identify risk factors.

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    Case report. A 75-year-old woman with a medical history of rheumatoid arthritis treated with hydroxychloroquine HCQ for about 10 years was admitted to our cardiac care unit with acute dyspnoea. The patient had no cardiovascular risk factors or known cardiovascular medical history. The diagnosis of hydroxychloroquine-induced cardiomyopathy was made based on the clinical, hemodynamic, and pathologic findings. This is the first case report describing chloroquine-induced cardiomyopa- thy involving the heart conduction system. Hydroxychloroquine-Induced Cardiomyopathy in Systemic Lupus Erythematosus; Peripheral Vascular Disease in Systemic Lupus Patients; Fatal Antimalarial-Induced Cardiomyopathy Report of 2 Cases; Basic Science for the Clinician 53 Mast Cells; Refractory Urticarial Vasculitis as a Complication of Ulcerative Colitis Successfully Treated With Rituximab

     
  7. DmitryDV1 Well-Known Member

    Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Hydroxychloroquine - Wikipedia Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Rx Side Effects New Plaquenil Guidelines and More.
     
  8. balcon User

    Plaquenil - FDA prescribing information, side effects and uses Mechanism of action The precise mechanism by which hydroxychloroquine exhibits activity against Plasmodium is not known. Hydroxychloroquine, like chloroquine, is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme.

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  9. Gendolf Well-Known Member

    Natural" alternative to Plaquenil. - HealthBoards Dec 29, 2004 "Natural" alternative to Plaquenil. I "know" I need some meds, but cannot tolerate Plaquenil. Wondering if anyone has come across something "natural" that mimics it.

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