One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Info plaquenil Side effects of plaquenil for rheumatoid arthritis In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. The condition sometimes resembles a target, or bulls-eye ring, on the retina surrounding the macula. PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. For radical cure of P. vivax and P. malariae infections, concomitant therapy with an 8-aminoquinoline compound is necessary. With Plaquenil Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 400 mg of Plaquenil daily puts anyone under 135 pounds at a higher risk for toxicity Therefore, 200mg of Plaquenil daily is going to be a safe dosage for virtually all adults13 It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Maculopathy plaquenil How to Succeed in Plaquenil Screenings, Plaquenil Dosage Guide - Plaquenil work for fibromyalgiaHydroxychloroquine side effects clinial studiesDangers of plaquenil in halfWhy is plaquenil prescribed for lupus One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine-Induced Retinal Toxicity - American.. Early Plaquenil Toxicity Detected without Bull’s Eye.. Hydroxychloroquine retinopathy A review of imaging. Retinopathy has been reported to be higher when the maintenance dose is exceeded. Use For lupus erythematosus chronic discoid and systemic in patients who have not responded satisfactorily to drugs with less potential for serious side effects. Usual Adult Dose for Rheumatoid Arthritis Maculopathy, or macular degeneration, is a disease related to the central part of the retina, called macula. Maculopathy is characterized by a progressive loss of central vision, usually bilateral, that greatly impairs vision functions. Retinal toxicity of Plaquenil may manifest itself with subtle disturbances of the retinal pigment epithelium which may eventually lead to complete destruction of the macula in the form of bull’s-eye maculopathy.