I am concerned, and should have asked him about this, but thought about it after the fact... I had to off of Plaquenil in December after 2 months. I have heard that you need to stay out of the sun while on Plaquenil. I don't remember what the warnings were about the sun because I live in Michigan and we don't have much sun that time of year. Chloroquine and filipina clathrin mediated endocytosis Cellulitis of leg and plaquenil Plaquenil hydroxychloroquine Drugs That Rarely Cause Photosensitivity. Biologics, unless the patient developed drug-induced lupus while on a TNF inhibitor; CellCept mycophenolate motfetil On reading blurb about Plaquenil it says it may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Plaquenil. Use a sunscreen or wear protective clothing if you must be outside for more than a short time. Sunburn — red, painful skin that feels hot to the touch — usually appears within a few hours after too much exposure to ultraviolet UV light from sunshine or artificial sources, such as sunlamps. Intense, repeated sun exposure that results in sunburn increases your risk of other skin damage and certain diseases. I developed a rash on the back of my neck then all over my front from neck to pelvis area. One thing I would keep your eye on is if you develop a rash. Plaquenil and sunburn Drug-induced photosensitivity DermNet NZ, Getting sunburnt & plaquenil! • Versus Arthritis formerly. Plaquenil side effects heartHydroxychloroquine nursing teachingHydroxychloroquine sulfate for hair loss Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells a special type of white blood cell which through a convoluted and boring process, causes inflammation. Inflammatory Osteoarthritis And Plaquenil. Sunburn - Symptoms and causes - Mayo Clinic. Effects of chronic exposure of hydroxychloroquine.. Photosensitivity is a common side-effect of methotrexate, plaquenil, and NSAIDs such as celebrex or advil. Photosensitivity may also be a serious side-effect of anti-TNF drugs such as cimzia, enbrel, humira, remicade, and simponi, as well as sulfasalazine. Lithium aggravates psoriasis in about half of those with psoriasis who take it. Antimalarials Plaquenil, Quinacrine, chloroquine and hydroxychloroquine may cause a flare of psoriasis, usually two to three weeks after the drug is taken. Hydroxychloroquine is the least likely to cause side effects. The reaction is often immediate. It usually occurs after the first dose of a drug and within 24 hours of taking the drug and exposure to the sun. Symptoms include severe redness on the areas of skin exposed to light, akin to an exaggerated sunburn with severe tenderness.