In fact, most people with lupus have fatigue at some point in their illness. “When lupus hit, it was like running into a wall at 80 mph,” says Ann S. How long does chloroquine take to work The making of chloroquine What are plaquenil deposits During my last visit, I told him I was struggling with fatigue, so he prescribed Plaquenil hydroxychloroquine. Plaquenil is an antimalarial medication that is also commonly prescribed for a variety of chronic illnesses. I take it to help combat fatigue, and the difference it makes is pleasantly surprising. Hi! I think Plaquenil is the cause of my extreme fatigue too. I am not anemic at this time and I get exhausted just trying to get through the day. I have also been on Plaquenil about three months. All of my arthritis swelling and pain are gone, but the fatigue will not let up! Hope things change for you. Plaquenil will also help with rashes. It does take awhile to build up in your system before you notice any results Make sure you see an eye doctor for a base line eye exam. If you use plaquenil there is a chance of a serious side effect, retinal damage.is important to get regular eye exams while you are taking this med. “I had been very active my whole life, and the fatigue just knocked me flat. Utterback, Ph D, a broadcast voice specialist in Virginia who was diagnosed with lupus in 2006. Plaquenil and fatigue Plaquenil for fatigue and pain DailyStrength, Is extreme fatigue a side effect of Plaquenil? 5 years for plaquenil to leave eyeItching from plaquenilStopping plaquenil during pregnancySanofi aventis plaquenilPlaquenil skin sloughing Hydroxychloroquine Plaquenil and generics can itself cause fatigue in some users, it can interrupt sleep patterns especially by causing more vivid dreams which in turn makes one more tired. The drug can also lower blood counts red cell, white cells and others too which in turn can cause fatigue. Is lethargy and tiredness a side effect of hydroxychloroquine?. Plaquenil and Fibromyalgia -. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. At doctor appointments, explain how fatigue affects you. Ask for lupus fatigue resources, and ask your doctor to support your efforts. Bring someone close to you to your next appointment. Listen to your body and understand your limits. Aerobic exercise is an effective non-drug treatment for lupus fatigue. Oct 23, 2005 Has anyone's doctor suggested Plaquenil for chronic fatigue syndrome? My rheumy has a couple of times. He says it could help with energy level because it is an immune enhancer. My mother took it for rheumatoid arthritis years ago and thinks it's worth a shot. My only concern is the. I've been on Plaquenil now for three months and its starting to help with the pain although I have diarrhoea every day but it's manageable. But I'm really struggling with fatigue now - worse than its ever been. Don't know whether its the RA itself or my body reacting to Plaquenil but I can't seem to do anything without being really really tired.