Although it is uncommon, lupus can also attack a patient’s liver, causing a more pronounced elevation in liver enzymes, such as ASTs and ALTs. When this happened to me, my symptoms included pervasive malaise, nausea, itching, and worsening of my overall health and lupus activity. Dosing plaquenil calculator Rash from taking plaquenil Plaquenil guidelines 2018 Plaquenil causing alopecia Liver enzyme abnormality was defined as a 10-fold or greater increase in aspartate aminotransferase and alanine aminotransferase. Acute toxic hepatitis was diagnosed, which rapidly returned to normal after cessation of the suspected causative medication, hydroxychloroquine, and subsequent administration of mycophenolate mofetil. I am another one with a diagnosis of UCTD. My symptoms most resemble lupus, but positive ANA is the only specifically associated test that is consistantly positive, other than off and on elevations in Sed rate, CRP and liver enzymes. I had one very mildly positive rheumatoid factor. I've been on Plaquenil for 3 years. Plaquenil has never raised my liver enzymes and I have been on it for six years. The only time my ALT and AST were elevated when I was taking too much iron supplements for my anemia. Once I stopped those, the enzymes went back to normal. They consulted and referred me to a gastroenterologist. My family doctor was persistent in finding an answer, and wouldn’t let my rheumatologist rest until they found one. Plaquenil and liver enzymes Hydroxychloroquine - LiverTox - NCBI Bookshelf, Plaquenil - What is chloroquine in lysosomesCan i take mucinex d with plaquenilGlioblastoma chloroquineChloroquine and malariaHow long until plaquenil side effects go away That I had high liver enzymes. All I want to do is sleep, I also hurt in my stomach most of the time. My urine is very dark I don t get hungry. I was on Nexuim but stopped. Can plaquenil cause liver damage Chronic liver damage causes Liver damage caused by iud. Can plaquenil cause liver damage - Doctor answers on.. Plaquenil and elevated liver enzymes? - Sjogren's World. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Can plaquenil cause liver damage. Premium Questions. loss of appetite, vomiting, clay colored feces, Lab tests showing raised liver enzymes, bilirubin. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Increased serum level of liver enzymes is a common finding in patients with systemic lupus erythematosus SLE. Hepatotoxic drugs, viral hepatitis and fatty liver are thought to be the main causes of hepatic lesion in these patients.